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Epidural Anesthesia (EA) with levobupivacaine 0.1% fentanyl (2mcg/ml) was effective at 5ml/h for postoperative analgesia.
The EA of 2-5ml/h was recontinued and effective for pain control for 3 days without no incident.
It is the first time in the medical literature that Lipid Emulsion is used for the purpose of LAR (Local Anesthesia Reversal) not connected to LAST (Local Anesthetic Systemic Toxicity).
Patients were randomly allocated to DXM group or Saline group.
DMT group received hyperbaric bupivacaine 0.5% (1.2 ml) (6 mg) in dextrose 8% solution DMT 0.3 ml (3 µg)－in total, bupivacaine 0.4% (1.5 ml) intrathecally and Saline group received hyperbaric bupivacaine 0.5% (1.2 ml) (6 mg) in dextrose 8% solution normal saline 0.3 ml －in total, bupivacaine 0.4% (1.5 ml) intrathecally.
On examination, she had diminished both touch sensory and motor power on the non-operative leg, but intact on the operative side with VAS at 2/10.
Epidural catheter was receded 2 cm and the dose was lowered and paused.Thus, intrathecal additive is frequently administer with local anesthetic to improve analgesic effect.Dexmedetomidine(DXM), a selective 2-adrenoreceptor agonist, has been used in the epidural space in humans without any reports of neurological deficits.Previous clinical studies showed that intravenous dexmedetomidine administration prolonged the sensory and motor blocks of bupivacaine spinal analgesia.But clinical studies about the use of intrathecal DXM with local anesthesia in humans are scarce in the literature. found that 3μg DXM added to 12 mg spinal bupivacaine produced the significant short onset of sensory and motor block as well as significantly longer duration of sensory and motor block than bupivacaine. reported that intrathecal dexmedetomidine as an adjuvant to 12.5mg bupivacaine in spinal anesthesia has a dose dependant effect on the onset and regression of sensory and motor block.The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Most patients undergoing TURP are elderly and frequently present with cardiopulmonary and endocrine diseases.Listing a study does not mean it has been evaluated by the U. Low-dose local anesthetic is commonly administer to limit the block level to minimize the hemodynamic changes.After spinal block, the level of sensory block, defined as the dermatomal segment with loss of pain sensation to pin-prick with a 22 G hypodermic needle and cold sensation to alcohol swab was measured every 2 min after intrathecal injection. The investigators recorded the peak sensory block level, time to peak block level from intrathecal injection, blood pressure and heart rate, and analgesic supplementation during operation. Effects of intrathecal dexmedetomidine on low-dose bupivacaine spinal anesthesia in elderly patients undergoing transurethral prostatectomy. Past medical history was hypertension, type 2 diabetes, bilateral degenerative knee pain.Spinal Anesthesia (SA) with 10 mg bupivacaine 0.5% heavy 20mcg fentanyl was effective for surgery.