Severe dengue was first recognized in the 1950s during dengue epidemics in the Philippines and Thailand.
Today, severe dengue affects most Asian and Latin American countries and has become a leading cause of hospitalization and death among children and adults in these regions.
Other features of the disease include its epidemiological patterns, including hyper-endemicity of multiple dengue virus serotypes in many countries and the alarming impact on both human health and the global and national economies.
Dengue virus is transported from one place to another by infected travelers.
The number of cases reported increased from 2.2 million in 2010 to over 3.34 million in 2016.
Although the full global burden of the disease is uncertain, the initiation of activities to record all dengue cases partly explains the sharp increase in the number of cases reported in recent years.
The America, South-East Asia and Western Pacific regions are the most seriously affected.
Cases across the Americas, South-East Asia and Western Pacific exceeded 1.2 million in 2008 and over 3.34 million in 2016 (based on official data submitted by Member States).
In 2015, Delhi, India, recorded its worst outbreak since 2006 with over 15 000 cases.
The Island of Hawaii, United States of America, was affected by an outbreak with 181 cases reported in 2015 and ongoing transmission in 2016.