Aspirin has been with us for long time – the first documented reports of its use occurred over 2000 years ago.
That said, the aspirin may not be in the form that you instantly think of (ie, a tablet) but it has been used all the same.
Given that both sulphuric acid and acetic acid are highly soluble in water, the crude mixture was washed and vacuum filtered using water, and then recrystallized in water and ethanol to improve purity.
Despite the efforts, the final product still possesses a vinegar smell.
Aspirin is an analgesic, which means it has pain killing effects and it has been well documented that the ancient Egyptians used a special tea made out of willow bark to treat a number of ailments.
It is also a substance that is remarkably easy to synthesize in the lab.INTRODUCTION In experimental chemistry, especially synthetic, a lot of harmful solvents are used to improve reaction conditions and toxic by-products are often generated .These chemicals are a source of pollution and are hazardous to the ecosystem.With the conventional heating method, a 52.4% yield was obtained, while an 83.5% yield was obtained by microwave heating.The high-yielding microwave irradiation method also displayed higher purity with a melting temperature range of 128-132�C (lit.It is faster than the more traditional method of filtering under gravity.Recrystalisation involves dissolving a product in the minimum amount of hot solvent and then quickly cooling down this solvent.The scratching process gives the aspirin a crystalline surface on which it can grow.The melting point determination gives an idea of purity as the purer a substance is the more defined it’s melting point is.135�C), while the conventionally heated ASA melted between 126-129�C.Based on the results, one could suggest that microwave irradiation is a cleaner and more efficient way to produce acetyl salicylic acid.